Joint Health

/Joint Health

Joint Health

as low as $34.95

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An active lifestyle creates muscle and joint strain that often demands relief. Joint Health combines patented NEM® natural egg shell membrane with proteolytic enzymes and powerful antioxidants to support muscle and joint health. Clinical studies have shown the natural ingredients in this superior formulation to be effective in helping maintain healthy joints, promoting faster recovery from strenuous activity, and optimizing the body’s renewal processes. Joint Health includes M.E.D.S.™, a proprietary micronutrient blend formulated to deliver maximum results.**

Joint Health is the best anti-inflammatory product for joint healing, tissue rejuvenation and recovery after a workout or injury. This all natural, cutting edge product has clinically proven results within 7-10 days with NEM, natural eggshell membrane. Joint Health is not only a hyaluronic acid supplement but boost high amount of proteolytic enzymes for reducing lactic acid build up, inflammation, pain and swelling. Break up scar tissue and start rebuilding cartilage with our powerful antioxidant blend including boswellia, quercetin, resveratrol and SOD precursor system.

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Product Description

Having healthy joints is critical to enjoying all that life has to offer.

The more than 50 million Americans with joint discomfort will tell you that even regular activity can become difficult when joint tissues start to break down due to age, injury, and even regular physical activity. When joint tissues such as cartilage begin to break down faster than they can be rebuilt, it can result in inflammation, pain, swelling, and ultimately in joint problems such as osteoarthritis. The inflammation associated with tissue degradation causes pain and swelling, and may actually speed the breakdown process. Providing the nutrients needed to build cartilage and minimize inflammation can be beneficial in combating this health concern.

Core Health Products’ Joint Health formula is a superior formulation that combines NEM® egg shell membrane with a proprietary blend of anti-inflammatory enzymes and an exclusive blend of antioxidant herbs and nutrients. These unique ingredients combine to support healthy cartilage formation, minimize cartilage degradation, and support the body’s natural healing processes.

NEM® Natural Egg Shell Membrane
This patented, natural egg shell membrane (NEM®) is a natural source of chondroitin sulfate, hyaluronic acid, collagen, and other glycosaminoglycans essential for healthy joints. Unlike glucosamine, which can take up to 60 days to produce an effect, NEM® has been clinically proven to provide relief in just 7-10 days. These superior, clinically proven results are what lead Core Health Products’ scientists to feature this ingredient as a core part of the Joint Health formula.

Proprietary Enzyme Blend
Protease enzymes support the natural healing processes and efficiency of the body in rebuilding damaged areas. Core Health Products’ Proprietary Enzyme blend includes a combination of protease enzymes, with two different proteases and bromelain. Bromelain is a special combination of protease enzymes derived from pineapple that has been shown to modulate the chemical messengers of the immune system associated with pain and inflammation. This advanced combination of enzymes provides anti-inflammatory benefits and helps improve recovery from exercise.

Proprietary Antioxidant & Herbal Blend
Grape seed extract, resveratrol, and quercetin are well-known antioxidants that have been researched for their benefits in modulating the body’s inflammatory processes, promoting recovery, and providing anti-aging benefits. Joint Health’s Proprietary Antioxidant Blend also includes an SOD precursor system made up of patented amino acid chelated copper, zinc, and manganese. These minerals are the building blocks your body requires to make more of its own super antioxidant enzyme – SOD (Super Oxide Dismutase). Vitamin C is critical for building and rebuilding cartilage, yet this critical nutrient is often low in the average diet. To ensure the body has all the building blocks for healthy joints, this blend includes a natural source of vitamin C (acerola cherry & rosehips) providing 200% of the daily value for vitamin C. Joint Health’s exclusive combination of potent antioxidant ingredients is combined with the powerful anti-inflammatory herb, Bowellia. This well-researched herb nutritionally supports the body’s healing processes and aids in recovery. These powerful ingredients also support the immune system’s natural anti-inflammatory processes.

Maximum Enzyme Delivery System (M.E.D.S.)
Every Core Health Products’ formula includes our proprietary nutrient delivery system known as M.E.D.S.™ This proprietary system uses the power of enzymes and fully-utilizable micronutrients to deliver maximum results.

The exceptional combination of ingredients in Core Health Products’ Joint Health helps to maintain healthy joints, promote faster recovery from exercise and competition, and optimize the body’s anti-inflammatory processes.

Key Benefits:

  • Promotes healthy muscles and joints.
  • Effectively supports the body in repairing tissue following an injury.
  • Enhances the body’s natural healing processes.
  • Optimizes the body’s anti-inflammatory processes.
  • Supports faster recovery from strenuous exercise and workouts.
  • Maximizes production of the body’s own powerful antioxidant enzyme (SOD) for even faster recovery.
  • Includes M.E.D.S. ™ to maximize results.

Joint Health Formula combines traditional joint health ingredients like boswellia with the power of proteolytic enzymes and the new, patented NEM® egg shell membrane to provide maximum benefits for joint health.

NEM® is a new ingredient derived from natural egg shell membrane. It is a natural source of chondroitin sulfate, hyaluronic acid, collagen, and other glycosaminoglycans essential for healthy joints. This patented ingredient has been clinically proven to provide results in just 7-10 days.*

Proprietary Enzyme Blend

  • Bromelain is a special combination of protease enzymes derived from pineapples. In addition to general protease effects, bromelain has been shown to modulate the chemical messengers of the immune system (cytokines and prostaglandins). By modulating the activity of these specific messengers, bromelain is able to provide a wide range of benefits for joint health, and potentially improve recovery from exercise.
  • Protease 4.5 and 6.0 are protease enzymes that break down large protein molecules into smaller proteins and amino acids. As a natural part of healing, proteins can build up in an area of injury. Protease enzymes help break up waste protein, thereby supporting the body’s natural process to more efficiently rebuild and support healthy muscles and joints. Protease 4.5 and 6.0 each work within different pH ranges. By combining these enzymes into the proprietary blend, Core Health Product’s Joint Health formula is able to provide a broad spectrum of enzyme activity and maximize the benefits of protease enzymes.

Proprietary Antioxidant and Herbal Blend

  • Acerola Cherry is an excellent natural source of vitamin C, a critical nutrient for joint health. The body cannot build or repair joint tissues without adequate amounts of vitamin C. Joint Health contains 200% DV of Vitamin C from acerola cherry to provide a truly balanced joint health formulation with all the necessary building blocks for healthy joints.
  • Boswellia, a close relative of frankincense (B. sacra), has been used for many thousands of years as an astringent and anti-inflammatory. Modern researchers have found that boswellia’s beneficial properties come both from its antioxidant capabilities and its unique ability to inhibit the production of leukotrienes (chemical messengers of the immune system) associated with inflammation. Numerous double-blind placebo-controlled clinical studies have shown its potential benefits for joint health.
  • Grape Seed Extract, is one of the most powerful natural sources of proanthocyanidins, which help protect tissues from free radicals produced in conditions of inflammation. The grape seed extract used in Joint Health utilizes a patented, environmentally friendly water-based extraction process. This process is able to recover more of the potent OPCs from grape seed than other extraction methods, and maintains the natural integrity and potency of proanthocyanidin antioxidants.
  • Quercetin is a bioflavanoid found naturally in the skin of apples, red onions, citrus fruits, and red grapes. Its antioxidant and anti-inflammatory properties play a key role in the maintenance and heath of collagen, a key component of cartilage and joint tissues.
  • Resveratrol is best known for its anti-aging properties, but it is a powerful non-flavanoid antioxidant found naturally in grapes and other plants, and has been researched for its various potential health benefits. It is thought to work by modulating the enzymes and signaling pathways involved in the body’s inflammation and aging processes.
  • SOD Precursor System: SOD, or SuperOxide Dismutase, is a powerful antioxidant enzyme produced by the body and fights inflammation and supports recovery. Unfortunately, SOD production and activity decreases with age and is often low in individuals with certain health conditions. Joint Health’s SOD Precursor System provides the nutrient building blocks needed to support the body’s ability to produce SOD.

References
Bromelain and Protease
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Akhtar NM, Naseer R, Farooqi AZ, Aziz W, Nazir M. Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee–a double-blind prospective randomized study. Clin Rheumatol. 2004 Oct;23(5):410-5. Epub 2004 Jul 24.

Kerkhoffs GM, Struijs PA, de Wit C, et al. A double blind, randomised, parallel group study on the efficacy and safety of treating acute lateral ankle sprain with oral hydrolytic enzymes. Br J Sports Med 2004;38:431-435.

Klein G, Kullich W, Schnitker J, Schwann H. Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clin Exp Rheumatol. 2006;24(1):25-30.

Szczurko O, Cooley K, Mills EJ, et al. Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial. Arthritis Rheum 2009;61:1037-1045.

Walker JA, Cerny FJ, Cotter JR, Burton HW. Attenuation of contraction-induced skeletal muscle injury by bromelain. Med Sci Sports Exerc. 1992 Jan;24(1):20-5.

[Oral enzyme therapy in osteoarthritis of the knee. Proteolytic enzyme are effective with few risks]. MMW Fortschr Med 143: 44-46, 2001.

Hale LP, Greer PK and Sempowski GD. Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation. Clin Immunol 104: 183-190, 2002.

 

Boswellia
Boswellia serrata. Monograph. Altern Med Rev. 2008 Jun;13(2):165-7.

Ammon HP. Modulation of the immune system by Boswellia serrata extracts and boswellic acids. Phytomedicine. 2010 Sep;17(11):862-7.

Banno N, Akihisa T, Yasukawa K, Tokuda H, Tabata K, Nakamura Y, Nishimura R, Kimura Y and Suzuki T. Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. J Ethnopharmacol 2006; 107(2):249-53.

Blain EJ, Ali AY, Duance VC. Boswellia frereana (frankincense) suppresses cytokine-induced matrix metalloproteinase expression and production of pro-inflammatory molecules in articular cartilage. Phytother Res. 2010 Jun;24(6):905-12.

Ernst E. Frankincense: systematic review. BMJ. 2008 Dec 17;337a2813. doi: 10.1136/bmj.a2813

Kimmatkar N, Thawani V, Hingorani L and Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee–a randomized double blind placebo controlled trial. Phytomedicine 10: 3-7, 2003.

Pungle P, Banavalikar M, Suthar A, Biyani M and Mengi S. Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb. Indian J Exp Biol 41: 1460-1462, 2003.

Siemoneit U, Pergola C, Jazzar B, Northoff H, Skarke C, Jauch J, Werz O. On the interference of boswellic acids with 5-lipoxygenase: mechanistic studies in vitro and pharmacological relevance. Eur J Pharmacol. 2009 Mar 15;606(1-3):246-54.

Grape Seed Extract
Carlson S, Peng N, Prasain JK, Wyss JM. Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females. Gend Med. 2008;5 Suppl A:S76-90.

Cho ML, et al. Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis. Immunol Lett. 2009 Jun 4;124(2):102-10.

Percival SS. Grape consumption supports immunity in animals and humans. J Nutr. 2009 Sep;139(9):1801S-5S.

Shi J, Yu J, Pohorly JE, Kakuda Y. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food. 2003 Winter;6(4):291-9.

Simonetti P, Ciappellano S, Gardana C, Bramati L, Pietta P. Procyanidins from Vitis vinifera seeds: in vivo effects on oxidative stress. J Agric Food Chem. 2002 Oct 9;50(21):6217-21.

Yilmaz Y, Toledo RT. Major flavonoids in grape seeds and skins: antioxidant capacity of catechin, epicatechin, and gallic acid. J Agric Food Chem. 2004 Jan 28;52(2):255-60.

Minerals of the SOD Precursor System
DiSilvestro RA, Marten J and Skehan M. Effects of copper supplementation on ceruloplasmin and copper-zinc superoxide dismutase in free-living rheumatoid arthritis patients. J Am Coll Nutr 11: 177-180, 1992

Kara E, Gunay M, Cicioglu I, Ozal M, Kilic M, Mogulkoc R, Baltaci AK. Effect of zinc supplementation on antioxidant activity in young wrestlers. Biol Trace Elem Res. 2010 Apr;134(1):55-63.

Mariani E, et al. Effects of zinc supplementation on antioxidant enzyme activities in healthy old subjects. Exp Gerontol. 2008 May;43(5):445-51

Rock E, Mazur A, O’connor JM, Bonham MP, Rayssiguier Y, Strain JJ. The effect of copper supplementation on red blood cell oxidizability and plasma antioxidants in middle-aged healthy volunteers. Free Radic Biol Med. 2000 Feb 1;28(3):324-9.

NEM® Egg Shell Membrane
NEM® White Paper. Natural Eggshell Membrane (NEM®) is a Natural Therapeutic Choice for Joint & Connective Tissue Disorder.

Ruff KJ et al. Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Clin Rheumatol 2009; 28:907-914.

Nakano T, Ikawa N, Ozimek L. Extraction of glycosaminoglycans from chicken eggshell. Poult Sci. 2001 May;80(5):681-4.

Nakano T, Ikawa N, Ozimek L. Galactosaminoglycan composition in chicken eggshell. Poult Sci. 2002 May;81(5):709-14.

Takahashi K, Shirai K, Kitamura M, Hattori M. Soluble egg shell membrane protein as a regulating material for collagen matrix reconstruction. Biosci Biotechnol Biochem. 1996 Aug;60(8):1299-302.

Wong M, Hendrix MJ, von der Mark K, Little C, Stern R. Collagen in the egg shell membranes of the hen. Dev Biol. 1984 Jul;104(1):28-36.

Quercetin
Boots AW, Drent M, de Boer VC, Bast A, Haenen GR. Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. Clin Nutr. 2011 Feb 14. [Epub ahead of print]

Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol. 2008 May 13;585(2-3):325-37.

Boots AW, Wilms LC, Swennen EL, Kleinjans JC, Bast A, Haenen GR. In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition. 2008 Jul-Aug;24(7-8):703-10.

Chirumbolo S. The role of quercetin, flavonols and flavones in modulating inflammatory cell function. Inflamm Allergy Drug Targets. 2010 Sep;9(4):263-85.

Choi EJ, Bae SC, Yu R, Youn J, Sung MK. Dietary vitamin E and quercetin modulate inflammatory responses of collagen-induced arthritis in mice. J Med Food. 2009 Aug;12(4):770-5.

Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys. 2010 Sep 1;501(1):79-90.

Davis JM, Carlstedt CJ, Chen S, Carmichael MD, Murphy EA. The dietary flavonoid quercetin increases VO(2max) and endurance capacity. Int J Sport Nutr Exerc Metab. 2010 Feb;20(1):56-62.

Davis JM, Murphy EA, Carmichael MD. Effects of the dietary flavonoid quercetin upon performance and health. Curr Sports Med Rep. 2009 Jul-Aug;8(4):206-13.

Egert S et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr. 2008 Sep;138(9):1615-21.

Resveratrol
Resveratrol. Monograph. Altern Med Rev. 2010 Jul;15(2):152-8.

Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 2006 Jun;5(6):493-506.

Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys. 2010 Sep 1;501(1):79-90.

Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A, Dandona P. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab. 2010 Sep;95(9):E1-8.

Guerrero RF, García-Parrilla MC, Puertas B, Cantos-Villar E. Wine, resveratrol and health: a review. Nat Prod Commun. 2009 May;4(5):635-58.

Kovacic P, Somanathan R. Multifaceted approach to resveratrol bioactivity: Focus on antioxidant action, cell signaling and safety. Oxid Med Cell Longev. 2010 Mar-Apr;3(2):86-100
.
Queen BL, Tollefsbol TO. Polyphenols and aging. Curr Aging Sci. 2010 Feb;3(1):34-42.

Zhang Z, Lowry SF, Guarente L, Haimovich B. Roles of SIRT1 in the acute and restorative phases following induction of inflammation. J Biol Chem. 2010 Dec 31;285(53):41391-401..

Vitamin C, Acerola Cherry, & Rose Hips
Christensen R, Bartels EM, Altman RD, Astrup A, Bliddal H. Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?–a meta-analysis of randomized controlled trials. Osteoarthritis Cartilage. 2008 Sep;16(9):965-72.

Jensen NH. [Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice]. Ugeskr Laeger. 2003 Jun 16;165(25):2563-6. [Article in Danish]

Motohashi N et al. Biological activity of barbados cherry (acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions. Phytother Res. 2004 Mar;18(3):212-23.

Wang Y, Hodge AM, Wluka AE, English DR, Giles GG, O’Sullivan R, Forbes A, Cicuttini FM. Effect of antioxidants on knee cartilage and bone in healthy, middle-aged subjects: a cross-sectional study. Arthritis Res Ther. 2007;9(4):R66.

Winther K, Apel K, Thamsborg G. A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Scand J Rheumatol. 2005 Jul-Aug;34(4):302-8.

 

 

 

 

 

Recommended Usage: Take two capsules daily on an empty stomach.

Storage: Store closed in a cool, dry place.

Shelf Life: 1 year

Special Considerations

Special Considerations/Allergen Information

Allergens:
Contains egg shell membrane from egg. (Contains no milk, wheat, soy, peanuts, nuts, corn, fish, or shellfish.)

 

Drug/Nutrient Interactions:
If you are taking:

  • Blood thinning medications such as warfarin, coumadin, heparain, Plavix or aspirin: do not use Joint Health except under the direction of a physician. The ingredients of Joint Health may enhance the effects of these medications.
  • Sedative drugs such as benzodiazepine: bromelain might amplify their effect. Joint Health contains high levels of bromelain.

If you are taking medications, consult with your physician or pharmacist before making changes to your diet, exercise, or supplementation program.

Special Considerations/Contraindications:

  • Joint Health should not be used by those individuals with bleeding disorders.
  • Joint Health should be discontinued at least 7 days prior to surgery, but is helpful as nutritional support for recovery.
  • No studies of the ingredients in Joint Health have been conducted on pregnant or nursing women. Consult with your physician before using this product if you are pregnant or nursing.

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